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These include itching, flushing, ulcers, and even low blood pressure.
Histamine is the same substance (or, at least, among the substances) released at the site of mosquito and other insect bites. In higher amounts, and when released more generally throughout the body, effects like those mentioned above become apparent.
But, those itching/flushing episodes aside, it makes my skin just generally itchy all the time (especially my feet and my scalp).
Some things that help mitigate the flushing episodes for me are: taking an aspirin 30-60 minutes before the niacin (recommended by my dr as by Quadop; and not taking the niacin/going to bed on an empty stomach.
If I remember to have a piece of fruit, crackers and cheese or half a PB sandwich before bed, I will thank myself in the morning.
They are used to treat and prevent stomach/small bowel ulcers and belong to the class of drugs called histamine-2 receptor anatagonists.Niacin, also called nicotinic acid, is actually a terrific drug for abnormal cholesterol and/or triglyceride levels.Indeed, niacin will tend to improve things regardless of the particular cholesterol or triglyceride abnormality that someone has. So, it's a shame that it has a number of side effects - most of a nuisance character, but some more serious.Anyway, the long-acting preparations are not just fairly expensive but, more importantly, have been associated with severe, fulminant liver disease (as well as less severe forms, too).As far as I know, that is always the case - it is not limited to a particular brand.